She graduated from Marquette's College of Engineering with a bachelor of science degree in biomedical engineering in 1978. She received her medical degree from the Medical College of Wisconsin in 1982. Her residency (1982–1985), her term as Chief Resident (1985–1986) and her Fellowship in Nephrology (1986–1988) were completed at Rush University Medical Center, Chicago.
Dr. Orlowski is currently chief operating officer and chief medical officer of MedStar Washington Hospital Center, Washington, D.C. The MedStar Health system includes nine hospitals and more than 100 clinics in the Baltimore-Washington region. The Hospital Center is one of the 20 largest hospitals in the United States, and is recognized for its cardiac care, burn, trauma, transplantation and cancer care. Dr. Orlowski oversees the medical staff, clinical care, quality, patient safety, medical risk, perioperative services, ambulatory care and the medical education programs.
Dr. Orlowski began her career at Rush as an intern. She left Rush as associate vice president and executive dean of the Rush University Medical School in Chicago.
Dr. Orlowski is board certified in both Internal Medicine and Nephrology. In her practice, she specializes in acute renal care and transplantation. She has been honored with teaching excellence awards, has participated in education and research in renal transplantation and has served on several national committees to oversee the quality of care in transplantation. Most recently, Dr. Orlowski chaired the national committee at UNOS (United Network for Organ Sharing) on transplant policy.
Dr. Orlowski has been the president of the Chicago Medical Society, and board member and chair of the Illinois State Medical Society. She served as editor of Disease-A-Month, and was on the editorial board of Nephrology.
In 2007 Dr. Orlowski was inducted as a Master in the American College of Physicians (ACP). This honor is bestowed on only a small minority of physicians in the United States.
In addition to her duties at the Hospital Center, Dr. Orlowski currently serves as chair of D.C. Board of Medicine, vice chair of the board of Catholic Charities of Washington and is also on the board of Montini Catholic High School in Lombard, Ill.
Dr. Orlowski and her husband, William McNulty (Eng '75), live in Georgetown, Washington, D.C. They have a second home in Keshena, Wis. Their son, Connor McNulty, is a recent graduate of Georgetown University.